HKUST Research Team Analyzes Deep-Sea Coral Bathypathes pseudoalternata and Its Microbiome
A research team from The Hong Kong University of Science and Technology has conducted a hologenomic analysis of the deep-sea black coral Bathypathes pseudoalternata, revealing its reliance on symbiotic microbes for survival in extreme habitats. Published in Cell Host & Microbe, the study highlights the coral's genetic dependence on these microbes for essential nutrients and the stability of its microbiome, which aids in detoxification, nutrient synthesis, and antiviral defense. The researchers developed a framework for analyzing host genomics and microbial profiles, successfully assembling a high-quality genome with 16 chromosomes.

A research team led by Prof. QIAN Peiyuan from The Hong Kong University of Science and Technology (HKUST) has conducted a hologenomic analysis of the deep-sea black coral Bathypathes pseudoalternata (B. pseudoalternata) in collaboration with the Southern Marine Science and Engineering Guangdong Laboratory and the Yellow Sea Fisheries Research Institute.
The study, published in Cell Host & Microbe, reveals how B. pseudoalternata survives in extreme habitats through microbiome interactions. The researchers developed an analytical framework to explore host genomics and microbial profiles, successfully assembling a high-quality genome with 16 chromosomes.
Findings indicate a genetic reliance on symbiotic microbes for essential nutrients due to the coral's lack of complete biosynthetic pathways. Microbial analyses showed a stable microbiome critical for the coral's survival, with symbionts providing detoxification, nutrient synthesis, and antiviral defense.



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